Group H of this season’s competition is the most interesting by far, with Man United currently level on nine points with both Leipzig and Paris St. Germain (PSG).
The 3-1 win at the London Stadium last week should act as inspiration for Solskjaer’s men, second-half goals from Marcus Rashford, Mason Greenwood and Paul Pogba seeing off West Ham.
However, Solskjaer will have to deal with a somewhat tense dressing room, following news Pogba is ‘unhappy’ at the club.
Raiola did not confirm whether Pogba would leave in January or the end of the season.
Solskjaer said the striking duo of Edinson Cavani and Anthony Martial were substituted during Saturday’s win due to muscle injuries.
Luke Shaw is back in training and could feature in a back-three defence, with Harry Maguire and Victor Lindelof.
Bruno Fernandes is a guaranteed starter due to the impact he’s had at the club since signing in January, with Scott McTominay also gunning for a starting position. McTominay and Fred have been vital in stabilising Man United’s midfield.
Mason Greenwood is in fine form again and could feature in a front-two with Marcus Rashford.
RB Leipzig vs Manchester United kicks off at 11:00 East African Time.
Predicted Manchester United starting lineup vs RB Leipzig:
David De Gea; Aaron Wan-Bissaka, Victor Lindelof, Harry Maguire, Luke Shaw, Alex Telles; Nemanja Matic, Scott McTominay, Bruno Fernandes; Marcus Rashford, Mason Greenwood